Cell Death and Fibrogenesis
نویسندگان
چکیده
منابع مشابه
Stressing fibrogenesis in cell culture.
Inhaled fibrous particles deposited in the lung periphery elicit a chronic inflammatory response that leads to production of fibrogenic mediators (1, 2). The fibrogenesis observed in asbestosis or silicosis, despite differences in histopathologic appearance, leads to similar disruptions in lung architecture, with deposition of extracellular matrix and cell proliferation characteristic of inters...
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Schnaper, H. William, Tomoko Hayashida, Susan C. Hubchak, and Anne-Christine Poncelet. TGFsignal transduction and mesangial cell fibrogenesis. Am J Physiol Renal Physiol 284: F243–F252, 2003; 10.1152/ajprenal.00300.2002.—Transforming growth factor(TGF) is closely associated with progressive renal fibrosis. Significant progress has been accomplished in determining the cellular signaling pathways...
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An exquisite equilibrium between cell proliferation and programmed cell death is required to maintain physiological homeostasis. In inflammatory bowel disease, and especially in Crohn's disease, enhanced proliferation along with defective apoptosis of immune cells are considered key elements of pathogenesis. Despite the relatively limited attention that has been given to research efforts devote...
متن کاملFibrogenesis
A review of fibrogenesis by asbestos fibers is given. There is nothing to indicate that the fibrogenic effects of inhaled asbestos fibers should differ in any way from those of ingested asbestos. Recently, ingestion has assumed some importance concerning human exposure. Three sections dealing with the process of fibrogenesis are covered: the first deals with in vitro fibrogenesis, in particular...
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Fibrosis is the pathological condition resulting in the growth of excess fibrous connective tissue in an organ or body system as a reparative or reactive process. In the field of clinical pathology, clinicians and medical scientists are endeavoring to translate experimental knowledge into effective, innovative treatments for a range of fibrotic conditions. The amelioration of whole organ functi...
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ژورنال
عنوان ژورنال: Seminars in Liver Disease
سال: 2010
ISSN: 0272-8087,1098-8971
DOI: 10.1055/s-0030-1255352